Chun-Chieh WANG MD, PhD

Expert in Precision Radiotherapy

Proton and Photon radiotherapy for brain, lung and Gyn cancers. Combining RT with immunotherapy.

Specialty

Proton and Photon radiotherapy for brain, lung and Gyn cancers. Combining RT with immunotherapy.


Profile

Chun-Chieh Wang is an associate professor of the Department of Medical Imaging and Radiological Sciences at Chang Gung University, and the vice director of the Proton and Radiation Therapy Center of Chang Gung Memorial Hospital. Dr. Wang graduated from Taipei Medical University, and holds his Ph.D. degree in biomedical physics from the University of California, Los Angeles, USA.

Dr. Wang has dedicated his career to the treatment of brain, lung, and Gyn cancer by radiation therapy. He joins several clinical trials in cervical cancer treatment and focuses on the role of HPV in radiation response. His areas of research include the use of OCT (Optical Coherence Tomography) and MRI to monitor the changes of tumor microenvironment after irradiation. Radiation-induced changes of immune function and stem cell differentiation are other research fields of interests.


Successful Cases

Thoracic tumor: ~1600 cases

Gyn Cancer: ~1300 cases

Brain tumor: ~1200 cases (including ~500 cases for radiosurgery)

Education

1986/09 - 1993/06, MD, Taipei Medical University

2000/09 - 2005/06, PhD, Biomedical Physics, University of California at Los Angeles


Past Experiences

1997 - present, Attending Physician at CGMH

2006, BrainLab Radiosurgery training at Germany

2012, Proton training at MD. Anderson, US


Current Appointments

Attending Physician, Department of Radiation Oncology and Proton Center, Chang Gung Memorial Hospital


Honors

Young Investigator Travel Awards, Radiation Research Society, 2004

Dissertation Year Fellowship Award, Graduate Division, University of California, Los Angeles, 2004-2005

Scholar-in-Training Award, American Association of Cancer Research (AACR), 2005

Award of Radiation Treatment Paper, Cancer Prevention & Treatment Foundation, 2011

Major Publications

  1. Wang CC, Chou HH, Yang LY, Lin H, Liou WS, Tseng CW, Liu FY, Liou JD, Huang KG, Huang HJ, Huang EY, Chen CH,Chang TC, Chang CJ, Hong JH, Lai CH. A randomized trial comparing concurrent chemoradiotherapy with single-agent cisplatin versus cisplatin plus gemcitabine in patients with advanced cervical cancer: An Asian Gynecologic Oncology Group study. Gynecol Oncol. 137(3):462-7, Mar 2015. (SCI; IF= 3.774) CMRPG380471
  2. Chen KT, Wu TW, Chuang CC, Hsu YH, Hsu PW, Huang YC, Lin TK, Chang CN, Lee ST, Wu CT, Tseng CK, Wang CC, Pai PC,Wei KC, Chen PY. Corpus callosum involvement and postoperative outcomes of patients with gliomas. J Neurooncol.  124(2):207-14; Sep 2015. (SCI; IF:5.562)
  3. Chao TC, Tsai YC, Chen SK, Wu SW, Tung CJ, Hong JH, Wang CC, Lee CC. An MCNPX2.7.0 study of Bragg peak degradation owing to density heterogeneity patterns for a CGMH therapeutic proton beam. Radiation Physics and Chemistry. Epub, Jan 2016. (SCI; IF:1.380)
  4. Lin Gigin, Lai CH, Tsai SY, Lin YC, Huang YT, Wu RC, Yang LY, Lu HY, Chao A, Wang CC, Ng KK, Ng SH, Chou HH, Yen TC, Hong JH. 1H MR spectroscopy in Cervical Carcinoma using External Phase Array Body Coil at 3.0T: Prediction of Poor Prognostic Human Papillomavirus (HPV) Genotypes. Journal of Magnetic Resonance Imaging, Epub, Jul 2016(SCI; IF:3.210)
  5. Ho CH, Fang YH, Chung HW, Yen TC, Ho TY, Chou HH , Hong JH, Huang YT , Wang CC*, Lai CH. A preliminary investigation into textural features of intratumoral metabolic heterogeneity in 18F-FDG PET for overall survival prognosis in patients with bulky cervical cancer treated with definitive concurrent chemoradiotherapy. Am J Nucl Med Mol Imaging 6(3): 166-75; 2016. (SCI; IF:2.520) CMRPG380671
  6. Chen FH, Wang CC, Liu HL, Fu SY, Yu CF, Chang C, Chiang CS, Hong JH. Decline of Tumor Vascular Function as Assessed by Dynamic Contrast-Enhanced Magnetic Resonance Imaging Is Associated With Poor Responses to Radiation Therapy and Chemotherapy. Int J Radiat Oncol Biol Phys. 95(5):1495-503; Aug 2016. (SCI; IF:4.258)
  7. Liu FY, Lai CH, Yang LY, Wang CC, Lin G, Chang CJ, Chang WY, Huang SH, Huang YE, Peng NJ, Hong JH, Chao A, Chou HH, Chang YC, Yen TC. Utility of(18)F-FDG PET/CT in patients with advanced squamous cell carcinoma of the uterine cervix reciving concurrent chemoradiotherapy: a parallel study of a prospective randomized trial. Eur J Nucl Med Mol Imaging. 43(10):1812-23;Sep 2016. (SCI; IF:5.383)
  8. Hsieh CE, Lin CY, Lee LY, Yang LY, Wang CC, Wang HM, Chang JT, Fan KH, Liao CT, Yen TC, Fang KH, Tsang YM. Adding concurrent chemotherapy to postoperative radiotherapy improves locoregional control but Not overall survival in patients with salivary gland adenoid cystic carcinoma-a propensity score matched study. Radiat Oncol. 11:47; Mar 2016. (SCI; IF:2.546)
  9. Tsai MT, Lee IC, Lee ZF, Liu HL, Wang CC, Choia YC, Chou HY, Lee JD. In vivo investigation of temporal effects and drug delivery induced by transdermal microneedles with optical coherence tomography. Biomedical Optics 7(5):1865-76; May 2016.(SCI; IF:2.859)