Lun-Jou LO MD

Craniofacial surgery

Cleft lip and palate, Craniofacial deformity, Orthognathic surgery, Facial cosmetic surgery

Profile

Dr. Lun-Jou Lo is an expert in cleft lip/palate surgery, aesthetic surgery, craniomaxillofacial surgery, orthognathic surgery, facial contouring surgery, 3D medical imaging, surgical simulation, 3D printing, and outcome assessment. He is Professor in Plastic and Reconstructive Surgery, Director of the Image Lab and Craniofacial Research Center, and Chairman of the Department of Surgery, Chang Gung Memorial Hospital, Linkou Medical Center, and Chang Gung University, Taiwan.

Dr. Lo graduated from Medical School of National Taiwan University. He received residency training in general surgery for 3 years and in plastic and reconstructive surgery for another 3 years. After 4 years of intensive surgical practice and training under Dr. Noordhoff and Dr. Yu-Ray Chen, he continued his learning in the St. Louis Children’s Hospital, Washington University Medical Center, Missouri, US in 1993. In St. Louis, he spent 2 years working with Dr. Jeffrey Marsh in the field of craniofacial surgery and 3-dimensional imaging study.

Dr. Lo has worked closely with the craniofacial team for cleft and maxillofacial patients. The team includes plastic surgeons, orthodontists, speech-language specialists, social worker, nursing specialist, as well as coordinator. Patients were followed up regularly. The multidisciplinary team is effective and supportive to the patients in Taiwan. This team also works in collaboration with the Noordhoff Craniofacial Foundation to provide comprehensive care in domestic as well as international patients. The team has provided many missions to the surrounding countries for patients with cleft lip/palate and craniofacial anomalies since 1998. The Chang Gung Craniofacial Center has trained numerous doctors and related healthcare specialists from other countries. A renowned activity is the yearly forum for cleft lip cleft palate and the orthognathic surgery, which attracted hundreds of participants from many countries.

Dr. Lo has published more than 160 peer-review scientific articles and authored several book chapters. He has been invited by international societies and centers for lecturing and surgical demonstration. He has received honorable awards and honored professorship from other countries. The Craniofacial Imaging Lab and the Craniofacial Research Center has specialized in 3D imaging for assessment, planning, surgical simulation, 3D printing and validation. The works resulted in numerous publications in the distinguished journals. The medical imaging has improved the treatment outcome in restoring patients’ function and facial appearance.

Specialty

Plastic & Reconstructive Surgery, cleft lip and palate surgery, orthognathic surgery, facial bone contouring surgery, rhinoplasty, facial cosmetic surgery

Successful Cases

Success rate for the cleft lip and palate repair are 100%. 3D simulation was used for orthognathic surgery with better occlusion, facial symmetry, midline adjustment, and facial esthetic outcome.

Education

(1) 1975–1982:  Medical College of National Taiwan University, Taipei, Taiwan.

(2) 1993-1995:  Research fellow, Washington University Medical Center, St. Louis, Missouri, U.S.A.


Experiences

(1) Secretary General, Taiwan Cleft Palate-Craniofacial Association (1995-1997)

(2) Editor, Chang Gung Medical Journal (1998-2001)

(3) Chairman, Education Committee, Department of Surgery, Chang Gung Memorial Hospital (1999-2003)

(4) Council member, Committee of Medical Education, Chang Gung Memorial Hospital (1999-2003)

(5) Council member, Committee of Medical Quality Evaluation, Chang Gung Memorial Hospital (2000-2003)

(6) Council member, Committee of Hospital Affairs, Chang Gung Children Hospital (1999-2000, 2003)

(7) Council member, Committee of Animal Experiment, Chang Gung Memorial Hospital (2003)

(8) President, Chang Gung Golf Team, Chang Gung Memorial Hospital (2003)

(9) Secretary General, Committee of Quality Control, Taiwan Surgical Association (1999-2004)

(10)  Chairman, Education Committee, Department of Plastic & Reconstructive Surgery, Chang Gung Memorial Hospital (2002-2006)

(11)  Director, Craniofacial Center, Department of Plastic & Reconstructive Surgery, Chang Gung Memorial Hospital (2003-2006)

(12)  Director, Division of Pediatric Plastic Surgery, Chang Gung Children Hospital (2002-2006)

(13)  Chief Editor, Bulletin of Taiwan Surgical Association (2004-2006)

(14)  Director and Vice Chairman, Operating Room Committee, Chang Gung Memorial Hospital (2004-2006)

(15)  Council Member, Taiwan Society of Plastic and Reconstructive Surgery   (2005-2006, 2008-2013)

(16)  President (2008-2010) International Society of Simulation Surgery (ISSiS)

(17)  Council Member, Taiwan Skull Base Surgery Association (2006-2008)

(18)  Chairman, Department of Plastic & Reconstructive Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan (2006- 2009)

(19)  Council Member, Taiwan Cleft Palate-Craniofacial Association (2000-2009)

(20)  Executive Editor, Chang Gung Medical Journal (2002-2012)

(21)  Vice Chairman, Department of Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan (2009-2013)

(22)  President, Taiwan Cleft Palate-Craniofacial Association (2010-2013)

(23)  Council Member, Taiwan Surgical Association (2012-2016)

(24)  Associate Editor, Plastic & Reconstructive Surgery®, Member in PRS Editorial Board, International Partner Society.


Current Appointments

(1) Professor, Plastic & Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University, and the Ministry of Education, Taiwan.

(2) Chairman, Department of Surgery, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.

(3) Associate Editor, PRS Global Open.

(4) Executive Editor, Biomedical Journal.

(5) Executive editor, Journal of the Formosan Medical Association.

(6) Council Member, Taiwan Cleft Palate Craniofacial Association

(7) Director, Craniofacial Research Center, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan

(8) Secretary General and Treasurer, Asian Pacific Craniofacial Association.


Awards

1. Awarded Honorary Professor by the National Center for Maternal and Child Health, Ulaanbaatar, Mongolia, August 27, 2013.

2. Awarded Honorary Fellowship of the Royal College of Surgeons of Thailand. Pattaya, Thailand, July 11, 2014.

3. Gold award, Symbol of National Quality (SNQ), 2015. (www.snq.org.tw)

4. Taiwan Revealed Medical Elite, Discovery Channel, 2016-7-20.


Medical Contributions

1. Cleft surgery missions to Cambodia, Vietnam, Myanmar, Loas, Philippines, etc.

2. Surgical techniques in lip and palate repairs.

3. Improvement of speech problems in patients with cleft.

4. 3D simulation for orthognathic surgery.

Total of 163 papers published

Published papers from 2014-2017

  1. Liao YF, Lee YH, Wang R, Huang CS, Chen PK, Lo LJ, Chen YR.  Vomer flap for hard palate repair is related to favorable maxillary growth in unilateral cleft lip and palate.  Clin Oral Investig 18(4): 1269-76, 2014.
  2. Kim SG, Lim HS, Chang CN, Lo LJ*.  Jaw deviation and ankylosis caused by condylar osteochondroma: long term treatment outcome. J Oral Maxillofac Surg 72(3): 604.e1-14, 2014. (*Corresponding author)
  3. Heuze Y, Martinez-Abadias N, Stella JM, Arnaud E, Collect C, Fructuoso GG, Alamar M, Lo LJ, Boyadjiev SA, Rocco FD, Richtsmeier JT.  Quantification of facial skeletal shape variation in FGFR-related craniosynostosis syndromes.  Birth Defects Research Part A: Clinical and Molecular Teratology 100(4): 250-9, 2014. doi: 10.1002/bdra.23228.
  4.  Chiang WC, Lin HH, Huang CS, Lo LJ, Wan SY.  The cluster assessment of facial attractiveness using fuzzy neural network classifier based on 3D Moire Features.  Pattern Recognition 47(3): 1249-1260, 2014.
  5. David-Paloyo FP, Yang XC, Lin JL, Wong FH, Wu-Chou YH, Lo LJ*.  Lower lip pits: van der Woude or Kabuki syndrome?  Cleft Palate Craniofac J  51(6): 729-34, 2014. (*Corresponding author)
  6. Worasakwutiphong S, Chuang YF, Chang HW, Lin HH, Lin PJ, Lo LJ*.  Nasal changes after orthognathic surgery for patients with class III malocclusion and prognathism: Analysis using three-dimensional photography.  J Formos Med Assoc. 114(2): 112-23, 2015. doi: 10.1016/j.jfma.2014.10.003. (*Corresponding author) (Impact factor 1.968)
  7. Lin HH, Chuang YF, Weng JL, Lo LJ*.  Comparative validity and reproducibility study of various landmark-oriented reference planes in 3-dimensional computed tomographic analysis for patients receiving orthognathic surgery. PLoS One 2015 Feb 10; 10(2): e0117604. doi: 10.1371/journal.pone.0117604. eCollection 2015. (*Corresponding author) (Impact factor 3.234)
  8. Lin HH, Lo LJ*.  Three-dimensional computer-assisted surgical simulation and intraoperative guidance in orthognathic surgery: a literature review. J Formos Med Assoc  114(4): 300-307, 2015. doi: 10.1016/j.jfma.2015.01.017. (*Corresponding author) (Impact factor 1.968)
  9. Fayyaz GQ, Gill NA, Ishaq I, Ganatra MA, Mohmood F, Kashif M, Alam I, Chen P, Lo LJ, Laub DR.   A model humanitarian cleft mission: 312 cleft surgeries in 7 days.  Plast Reconstr Surg Glob Open. 2015 Apr 7;3(3):e313. doi: 10.1097/GOX.0000000000000282. eCollection 2015 Mar. PMID: 25878924
  10. Lin JL, Lee WI, Huang JL, Chen PK, Chan KC, Lo LJ, You YJ, Shih YF, Tseng TY, Wu MC.  Immunologic assessment and KMT2D mutation detection in Kabuki syndrome.  Clin Genet. 2015 Sep;88(3):255-60. doi: 10.1111/cge.12484. (Impact factor 3.931)
  11.  Lin HH, Chang HW, Wang CH, Kim SG, Lo LJ*.  Three-dimensional computer-assissted orthognathic surgery: experience of 37 patients.  Ann Plast Surg  2015 May;74 Suppl 2:S118-26. doi: 10.1097/SAP.0000000000000455. (*Corresponding author) (Impact factor 1.494)
  12. Yang WM, Ho CT, Lo LJ*.  Automatic superimposition of palatal fiducial markers for accurate integration of digital dental model and cone beam computed tomography. J Oral Maxillofac Surg. 2015 Aug; 73(8):1616.e1-10. doi: 10.1016/j.joms.2015.04.004. (*Corresponding author) (Impact factor 1.425)
  13. Ke CY, Xiao WL, Chen CM, Lo LJ*, Wong FH*.  IRF6 is the mediator of TGFβ3 during regulation of the epithelial mesenchymal transition and palatal fusion. Scientific Reports  2015 Aug 4;5:12791. doi: 10.1038/srep12791 (*Corresponding author) (Impact factor 5.578)
  14. Hsu PJ, Wang SH, Yun C, Lo LJ*.  Redo double opposing z-plasty is effective for correction of marginal velopharyngeal insufficiency.  J Plast Reconstr Aesthet Surg. 2015 Sep; 68(9):1215-20. doi: 10.1016/j.bjps.2015.05.014. (*Corresponding author) (Impact factor 1.421)
  15. Chang HW, Lin HH, Chortrakarnkij P, Kim SG, Lo LJ*.  Intraoperative navigation for single-splint two-jaw orthognathic surgery: From model to actual surgery.  J Craniomaxillofac Surg. 2015 Sep; 43(7):1119-26. doi: 10.1016/j.jcms.2015.06.009.  (*Corresponding author) (Impact factor 2.933)
  16. Lin HH, Chang HW, Lo LJ*.  Development of customized positioning guides using computer aided design and manufacturing technology for orthognathic surgery.  Int J Comput Assist Radiol Surg. 2015 Dec;10(12):2021-33. doi: 10.1007/s11548-015-1223-0. (*Corresponding author) (Impact factor 1.707)
  17. Lonic D, Lo LJ*.  3D simulation of orthognathic surgery- surgeon’s perspective.  J Formos Med Assoc. 2016, 115: 387-388. doi: 10.1016/j.jfma.2015.09.002. (*Corresponding author) (Impact factor 1.968)
  18. Huang SF, Lo LJ, Lin CL.  Biomechanical optimization of a custom-made positioning and fixing bone plate for Le Fort I osteotomy by finite element analysis.  Comput Biol Med. 2016 Jan 1; 68:49-56. doi: 10.1016/j.compbiomed.2015.10.015. (Impact factor 1.521)
  19. Yamaguchi K, Lonic D, Lo LJ*.  Complications following orthognathic surgery for patients with cleft lip/palate: A systematic review. J Formos Med Assoc  2016 Apr; 115(4) 269-77. doi: 10.1016/j.jfma.2015.10.009. (*Corresponding author) (Impact factor 1.968)
  20. Lonic D, Pai BC, Yamaguchi K, Chortrakarnkij P, Lin HH, Lo LJ*.  Computer-assisted orthognathic surgery for patients with cleft lip/palate: From traditional planning to three-dimensional surgical simulation. PLoS One. 2016 Mar 22;11(3):e0152014. doi: 10.1371/journal.pone.0152014. eCollection 2016. (*Corresponding author) (Impact factor 3.234)
  21. Yamaguchi K, Lonic D, Lee CH, Yun C, Lo LJ*.  Modified Furlow palatoplasty using small double-opposing Z-plasty: Surgical technique and outcome. Plast Reconstr Surg  2016 Jun;137(6):1825-31. doi: 10.1097/PRS.0000000000002181. (*Corresponding author) (Impact factor 3.087)
  22. Chang WJ, See LC, Lo LJ*.  Time trend of incidence rates of cleft lip/palate in Taiwan from 1994 to 2013. Biomed J 2016; 39: 150-154. doi:10.1016/j.bj.2015.10.003 (*Corresponding author) (Non-SCI)
  23. Lonic D, Morris D, Lo LJ*.  Primary overcorrection of the unilateral cleft nasal deformity: Quantifying the results. Ann Plast Surg 2016 Feb;77 Suppl 1:S25-9. doi: 10.1097/SAP.0000000000000708. (*Corresponding author) (Impact factor 1.535)
  24. Yamaguchi K, Lonic D, Lee CH, Wang SH, Yun C, Lo LJ*. A treatment protocol for velopharyngeal insufficiency and the outcome. Plast Reconstr Surg  2016 Aug; 138(2): 290e-9e. doi: 10.1097/PRS.0000000000002386. (*Corresponding author) (Impact factor 3.087).
  25. Huang SF, Lo LJ, Lin CL. Biomechanical interactions of different mini-plate fixations and maxilla advancements in the Le Fort I Osteotomy: a finite element analysis.  Comput Methods Biomech Biomed Engin. 2016 May 6:1-10. [Epub ahead of print] (Impact factor 1.850)
  26. Huang SF, Lo LJ, Lin CL.  Factorial analysis of variables influencing mechanical characteristics in the Le Fort I Osteotomy using FEA and statistics-based Taguchi method. Journal of Medical and Biological Engineering. DOI 10.1007/s40846-016-0157-5. Published online: 06 August 2016. (Impact factor 1.018)
  27. Yamaguchi K, Lonic D, Chen C, Lo LJ*.  Correction of facial deformity in Sturge-Weber syndrome.  Plast Reconstr Surg Glob Open 2016 Aug 15;4(8):e843. doi: 10.1097/GOX.0000000000000843. (*Corresponding author) (Non-SCI)
  28. Ho, CT, Lin HH, Liou EJW, Lo LJ*.  Three-dimensional surgical simulation improves the planning for correction of facial prognathism and asymmetry: A qualitative and quantitative study.  Scientific Reports 2017 Jan 10;7:40423. doi: 10.1038/srep40423.  (*Corresponding author) (Impact factor 5.228)
  29. Wang YT, Yu JH, Lo LJ, Hsu PH, Lin CL. Developing customized dental miniscrew surgical template from thermoplastic polymer material using image superimposition, CAD system, and 3D printing. Biomed Res Int. 2017;2017:1906197. doi: 10.1155/2017/1906197. PMID: 28280726. Epub 2017 Feb 9. (Impact factor 2.134)
  30. Lin HH, Kim SG, Kim HY, Niu LS, Lo LJ*.  Higher dose of dexamethasone does not further reduce facial swelling after orthognathic surgery: A randomized controlled trial using 3-dimensional photogrammetry.  Ann Plast Surg 2017 Mar;78(3 Suppl 2):S61-S69. doi: 10.1097/SAP.0000000000001008. PMID: 28118231. (*Corresponding author) (Impact factor 1.535)
  31. Chortrakarnkij P, Lonic D, Lin HH, Lo LJ*.  Establishment of a reliable horizontal reference plane for 3-dimensional facial soft tissue evaluation before and after orthognathic surgery.  Ann Plast Surg 2017 Mar;78(3 Suppl 2):S139-S147. doi: 10.1097/SAP.0000000000001020. PMID: 28195892. (*Corresponding author) (Impact factor 1.535)
  32. Chortrakarnkij P, Lonic D, Lin HH, Yamaguchi K, Kim SG, Lo LJ*.  A modified technique of mandibular ramus sagittal split osteotomy for prevention of inferior alveolar nerve injury: A prospective cohort study and outcome assessment. Ann Plast Surg  2017 Mar;78(3 Suppl 2):S108-S116. doi: 10.1097/SAP.0000000000001015. PMID: 28166135. (*Corresponding author) (Impact factor 1.535)
  33. Lin S, Hsiao YC, Huang JJ, Chang CS, Chen PK, Chen JP, Lo LJ, Chen YR. Minimal invasive rhinoplasty: fat injection for nasal dorsum contouring. Ann Plast Surg. 2017 Mar;78(3 Suppl 2):S117-S123. doi: 10.1097/SAP.0000000000001016. PMID: 28195887. (Impact factor 1.535)
  34. Ko EW, Chen PK, Lo LJ.  Comparison of the adult 3D craniofacial features of patients with unilateral craniofacial microsomia with and without early mandibular distraction. Int J Oral Maxillofac Surg. 2017 Mar 27. pii: S0901-5027(17)31346-2. doi: 10.1016/j.ijom.2017.03.002. [Epub ahead of print] (Impact factor 1.563)
  35. Lonic D, Sundoro A, Lin HH, Lin PJ, Lo LJ*.  Selection of a horizontal reference plane in 3D evaluation: Identifying facial asymmetry and occlusal cant in orthognathic surgery planning. Sci Rep. 2017 May 19;7(1):2157. doi: 10.1038/s41598-017-02250-w. PMID: 28526831. (*Corresponding author) (Impact factor 5.228)
  36. Wu TY, Lin HH, Lo LJ, Ho CT. Postoperative outcomes of two- and three-dimensional planning in orthognathic surgery: A comparative study. J Plast Reconstr Aesthet Surg. 2017 Aug;70(8):1101-1111. doi: 10.1016/j.bjps.2017.04.012. Epub 2017 Apr 23. PMID: 28528114. (Impact factor 1.743)
  37. Kuo HN, Mei HI, Liu TK, Liu TY, Lo LJ, Lin CL. In vitro laser treatment platform construction with dental implant thread surface on bacterial adhesion for peri-implantitis. BioMed Research International, vol. 2017, Article ID 4732302, 7 pages, 2017. doi:10.1155/2017/4732302. (Impact factor 2.476)